{"id":6083,"date":"2021-11-01T14:37:42","date_gmt":"2021-11-01T14:37:42","guid":{"rendered":"https:\/\/neuropmnet.gr\/?page_id=6083"},"modified":"2021-11-01T19:39:58","modified_gmt":"2021-11-01T19:39:58","slug":"description-2","status":"publish","type":"page","link":"https:\/\/neuropmnet.gr\/?page_id=6083&lang=en","title":{"rendered":"Description"},"content":{"rendered":"<div data-colibri-id=\"6083-c1\" class=\"style-1347 style-local-6083-c1 position-relative\">\n  <!---->\n  <div data-colibri-component=\"section\" data-colibri-id=\"6083-c2\" id=\"ti_gnorizoume\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-1348 style-local-6083-c2 position-relative\">\n    <!---->\n    <!---->\n    <div class=\"h-section-grid-container h-section-boxed-container\">\n      <!---->\n      <div data-colibri-id=\"6083-c3\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 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style-local-6083-c16-outer\">\n                                <div data-colibri-id=\"6083-c16\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-2145 style-local-6083-c16 position-relative\">\n                                  <!---->\n                                  <!---->\n                                  <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                                    <!---->\n                                    <div data-colibri-id=\"6083-c17\" class=\"h-text h-text-component style-2146 style-local-6083-c17 position-relative h-element\">\n                                      <!---->\n                                      <!---->\n                                      <div class=\"\">\n                                        <p>\u00a9 2021<\/p>\n                                      <\/div>\n                                    <\/div>\n                                  <\/div>\n                                <\/div>\n                              <\/div>\n                            <\/div>\n                          <\/div>\n                        <\/div>\n                      <\/div>\n                    <\/div>\n                    <div id=\"offcanvas-overlay-6083-c9\" class=\"offscreen-overlay style-2138-offscreenOverlay style-local-6083-c9-offscreenOverlay\"><\/div>\n                  <\/div>\n                <\/div>\n                <div data-colibri-id=\"6083-c18\" class=\"h-global-transition-all h-heading style-2189 style-local-6083-c18 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-2189 style-local-6083-c18\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">Generally<\/h4>\n                  <\/div>\n                <\/div>\n                <div data-colibri-id=\"6083-c19\" class=\"h-text h-text-component style-1377 style-local-6083-c19 justify-text position-relative h-element\">\n                  <!---->\n                  <!---->\n                  <div class=\"\">\n                    <p>Neurodegenerative diseases, due to the aging of the population, are an ever-increasing burden for patients and carers. In these diseases, there is a progressively deteriorating clinical picture, due to a progressive degeneration of\n                      the neurons of the Central Nervous System. Such diseases are Alzheimer&#8217;s disease (AL), other forms of dementia, such as frontotemporal dementia (MCA), Parkinson&#8217;s disease (NP), lateral myotrophic sclerosis (Kinetic Neuron Disease,\n                      NSC) and Huntington&#8217;s disease (NH). Also, multiple sclerosis, despite being a predominantly neuroimmune disease, has an undeniable neurodegenerative dimension. All these diseases affect a total of hundreds of thousands of Greek citizens\n                      and their families.<\/p>\n                  <\/div>\n                <\/div>\n                <div data-colibri-id=\"6083-c20\" class=\"d-block style-1379 style-local-6083-c20 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-image__frame-container-outer\">\n                    <div class=\"h-image__frame-container\">\n                      <!---->\n                      <!---->\n                      <img loading=\"lazy\" decoding=\"async\" width=\"626\" height=\"358\" src=\"http:\/\/neuropmnet.gr\/wp-content\/uploads\/2021\/04\/cropped-conceptual-illustration-neuron-cells-with-glowing-link-knots-neurons-brain-with-focus.jpg\" class=\"wp-image-2787 style-1379-image style-local-6083-c20-image\" alt=\"\" srcset=\"https:\/\/neuropmnet.gr\/wp-content\/uploads\/2021\/04\/cropped-conceptual-illustration-neuron-cells-with-glowing-link-knots-neurons-brain-with-focus.jpg 626w, https:\/\/neuropmnet.gr\/wp-content\/uploads\/2021\/04\/cropped-conceptual-illustration-neuron-cells-with-glowing-link-knots-neurons-brain-with-focus-300x172.jpg 300w, https:\/\/neuropmnet.gr\/wp-content\/uploads\/2021\/04\/cropped-conceptual-illustration-neuron-cells-with-glowing-link-knots-neurons-brain-with-focus-16x9.jpg 16w\" sizes=\"auto, (max-width: 626px) 100vw, 626px\" \/>\n                      <div class=\"h-image__frame h-hide-lg h-hide-md h-hide-sm style-1379-frameImage style-local-6083-c20-frameImage\"><\/div>\n                    <\/div>\n                  <\/div>\n                <\/div>\n                <div data-colibri-id=\"6083-c21\" class=\"h-text h-text-component style-1378 style-local-6083-c21 justify-text position-relative h-element\">\n                  <!---->\n                  <!---->\n                  <div class=\"\">\n                    <p>Research efforts in recent years have made it clear that the clinical-symptomatic phase of neurodegenerative diseases is preceded by an early &#8211; preclinical phase of 15-20 years (possibly longer) of neurodegenerative pathological lesions\n                      in the brain. Clinical deficits occur when the accumulation of such lesions has either mobilized additional biological pathways in the form of an avalanche, or has led to the destruction of a sufficient amount of neurobiological\n                      mass so that the mental reserves &#8211; stock are no longer sufficient. A better understanding of this long-term pre-symptomatic stage has been made possible through the development of neurodegenerative and other biomarkers in CNS, as\n                      well as imaging methods with new probes for neurodegenerative biomarkers and other neurobiological factors (especially PET and SPECT). This extended preclinical stage has been demonstrated in both sporadic and genetic forms of neurodegenerative\n                      diseases.<\/p>\n                    <p>Efforts to understand the preclinical stages continue unabated worldwide and simultaneously involve many approaches:<\/p>\n                  <\/div>\n                <\/div>\n                <div data-colibri-id=\"6083-c22\" class=\"icon-list d-flex justify-content-lg-center justify-content-md-center justify-content-center style-1393 style-local-6083-c22 position-relative h-element\">\n                  <!---->\n                  <ul class=\"ul-list-icon vertical-on-desktop vertical-on-tablet vertical-on-mobile justify-content-lg-center justify-content-md-center justify-content-center\">\n                    <!---->\n                    <li class=\"list-item no-gutters\">\n                      <!---->\n                      <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center first-el-spacer\"><\/div> <span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-1393-icon style-local-6083-c22-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n                <span class=\"list-text d-block\"><span>the most complete biological understanding of pathways and mechanisms<\/span><\/span>\n              <\/div>\n              <\/span>\n              <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n                <!---->\n              <\/div>\n              <\/li>\n              <li class=\"list-item no-gutters\">\n                <!---->\n                <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-1393-icon style-local-6083-c22-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n            <span class=\"list-text d-block\"><span>the renewal of the diagnostic criteria of neurodegenerative diseases and<\/span><\/span>\n          <\/div>\n          <\/span>\n          <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n            <!---->\n          <\/div>\n          <\/li>\n          <li class=\"list-item no-gutters\">\n            <!---->\n            <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-1393-icon style-local-6083-c22-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n        <span class=\"list-text d-block\"><span>testing new potential therapies as early as possible, in the hope of greater effectiveness.<\/span><\/span>\n      <\/div>\n      <\/span>\n      <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\" style=\"display: none;\">\n        <!---->\n      <\/div>\n      <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center last-el-spacer\"><\/div>\n      <\/li>\n      <\/ul>\n    <\/div>\n    <div data-colibri-id=\"6083-c23\" class=\"h-text h-text-component style-1392 style-local-6083-c23 justify-text position-relative h-element\">\n      <!---->\n      <!---->\n      <div class=\"\">\n        <p>There is already a revolution in the field of monogenic diseases in Neurology, as rapidly targeted, individualized therapies are being developed to address specific genetic forms of neurological diseases, particularly neurodegenerative ones. In\n          most cases, these are treatments that are in the Clinical Trials phase, but are expected to be available on a wider basis in the coming years for patients with monogenic neurodegenerative diseases. It is important to identify patients who are\n          in the early stages of these conditions so that they are ready to receive these future targeted therapies.<\/p>\n        <p>Today in Greece there are a number of studies that have focused on early &#8211; preclinical diagnosis of neurodegenerative diseases. In addition, there are Centers that carry out a systematic recording of cases of neurodegenerative diseases, and maintain\n          collections of biological material. Studies are being done in this biological material, in order to make a more accurate diagnosis and in some cases, such as multiple sclerosis, to weigh the response to treatment with nosocomial treatments.\n          Efforts are also being made to develop new biological markers, as well as to develop models of neurodegenerative diseases at the cellular or animal model level, in order to test innovative therapeutic approaches.<\/p>\n        <p>In this context, the present Action of the National Medical Precision Network targets 3 Axes.<\/p>\n      <\/div>\n    <\/div>\n    <div data-colibri-id=\"6083-c24\" class=\"icon-list d-flex justify-content-lg-center justify-content-md-center justify-content-center style-1385 style-local-6083-c24 position-relative h-element\">\n      <!---->\n      <ul class=\"ul-list-icon vertical-on-desktop vertical-on-tablet vertical-on-mobile justify-content-lg-center justify-content-md-center justify-content-center\">\n        <!---->\n        <li class=\"list-item no-gutters\">\n          <!---->\n          <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center first-el-spacer\"><\/div> <span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-1385-icon style-local-6083-c24-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n    <span class=\"list-text d-block\"><span>Creation of a Register of Neurodegenerative Diseases and their Precursor Forms<\/span><\/span>\n  <\/div>\n  <\/span>\n  <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n    <!---->\n  <\/div>\n  <\/li>\n  <li class=\"list-item no-gutters\">\n    <!---->\n    <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-1385-icon style-local-6083-c24-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n<span class=\"list-text d-block\"><span>Creation of a Biological Material Bank of Neurodegenerative Diseases and Their Precursor Forms-Biochemical and Molecular Analysis of Biological Material Aiming at Precision Medicine<\/span><\/span>\n<\/div>\n<\/span>\n<div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n  <!---->\n<\/div>\n<\/li>\n<li class=\"list-item no-gutters\">\n  <!---->\n  <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-1385-icon style-local-6083-c24-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n  <span class=\"list-text d-block\"><span>Development of cellular and animal models, as well as new biological markers for neurodegenerative diseases<\/span><\/span>\n  <\/div>\n  <\/span>\n  <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\" style=\"display: none;\">\n    <!---->\n  <\/div>\n  <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center last-el-spacer\"><\/div>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div data-colibri-id=\"6083-c25\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-2264 style-local-6083-c25 position-relative\">\n  <!---->\n  <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n    <!---->\n    <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-2265-outer style-local-6083-c26-outer\">\n      <div data-colibri-id=\"6083-c26\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-2265 style-local-6083-c26 position-relative\">\n        <!---->\n        <!---->\n        <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n          <!---->\n          <div data-colibri-id=\"6083-c27\" class=\"h-divider style-2201 style-local-6083-c27 position-relative h-element\">\n            <!----><span class=\"h-divider__line style-2201-line style-local-6083-c27-line style-2201-line style-local-6083-c27-line\"><\/span><\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>\n<\/div>\n<\/div>\n<div data-colibri-component=\"section\" data-colibri-id=\"6083-c32\" id=\"ti_einai\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-2158 style-local-6083-c32 position-relative\">\n  <!---->\n  <!---->\n  <div class=\"h-section-grid-container h-section-boxed-container\">\n    <!---->\n    <div data-colibri-id=\"6083-c33\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-2187 style-local-6083-c33 position-relative\">\n      <!---->\n      <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n        <!---->\n        <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-2188-outer style-local-6083-c34-outer\">\n          <div data-colibri-id=\"6083-c34\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-2188 style-local-6083-c34 position-relative\">\n            <!---->\n            <!---->\n            <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n              <!---->\n              <div data-colibri-id=\"6083-c35\" class=\"h-global-transition-all h-heading style-2189 style-local-6083-c35 position-relative h-element\">\n                <!---->\n                <div class=\"h-heading__outer style-2189 style-local-6083-c35\">\n                  <!---->\n                  <!---->\n                  <h4 class=\"\">What are Neurodegenerative Diseases?<\/h4>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n    <div data-colibri-id=\"6083-c36\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-2159 style-local-6083-c36 position-relative\">\n      <!---->\n      <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n        <!---->\n        <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-2161-outer style-local-6083-c37-outer\">\n          <div data-colibri-id=\"6083-c37\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-2161 style-local-6083-c37 position-relative\">\n            <!---->\n            <!---->\n            <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n              <!---->\n              <div data-colibri-id=\"6083-c38\" class=\"h-text h-text-component style-2182 style-local-6083-c38 justify-text position-relative h-element\">\n                <!---->\n                <!---->\n                <div class=\"\">\n                  <p>Neurodegenerative diseases (NE) are an umbrella term for a range of conditions that mainly affect neurons in the human brain and are usually recognized by symptoms such as reduced motor control, mood disorders and cognitive deficits.\n                    As the name suggests, conditions are characterized by neuronal degeneration. Neurons are nerve cells in the brain and spinal cord that are not usually reproduced or replaced.<span style=\"font-size: 98%;\"> <\/span>If the neurons are\n                    damaged, they can not recover, resulting in brain dysfunction and incurable diseases. Despite the similarities between neurodegeneration in the relevant situations, the origin of the causes may be different. Examples of SE include\n                    Parkinson&#8217;s, Alzheimer&#8217;s and Huntington&#8217;s disease.<\/p>\n                  <p>NA are incurable and debilitating conditions that lead to progressive degeneration and \/ or death of nerve cells. This causes problems with movement (called ataxia) or mental function (called dementia).<\/p>\n                  <p>Dementias are responsible for the greater severity of NA, with Alzheimer&#8217;s accounting for about 60-70% of dementia cases.<\/p>\n                  <p>The SEs that EDIAN focuses on are:<\/p>\n                <\/div>\n              <\/div>\n              <div data-colibri-id=\"6083-c39\" class=\"icon-list d-flex justify-content-lg-center justify-content-md-center justify-content-center style-2185 style-local-6083-c39 position-relative h-element\">\n                <!---->\n                <ul class=\"ul-list-icon vertical-on-desktop vertical-on-tablet vertical-on-mobile justify-content-lg-center justify-content-md-center justify-content-center\">\n                  <!---->\n                  <li class=\"list-item no-gutters\">\n                    <!---->\n                    <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center first-el-spacer\"><\/div> <span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-2185-icon style-local-6083-c39-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n              <span class=\"list-text d-block\"><span>Alzheimer&#8217;s disease (NA) and other forms of dementia<\/span><\/span>\n            <\/div>\n            <\/span>\n            <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n              <!---->\n            <\/div>\n            <\/li>\n            <li class=\"list-item no-gutters\">\n              <!---->\n              <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-2185-icon style-local-6083-c39-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n          <span class=\"list-text d-block\"><span>Parkinson&#8217;s disease (NP) and precursors<\/span><\/span>\n        <\/div>\n        <\/span>\n        <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n          <!---->\n        <\/div>\n        <\/li>\n        <li class=\"list-item no-gutters\">\n          <!---->\n          <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-2185-icon style-local-6083-c39-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n      <span class=\"list-text d-block\"><span>Motor Neuron Disease (CKD)<\/span><\/span>\n    <\/div>\n    <\/span>\n    <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n      <!---->\n    <\/div>\n    <\/li>\n    <li class=\"list-item no-gutters\">\n      <!---->\n      <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-2185-icon style-local-6083-c39-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n  <span class=\"list-text d-block\"><span>Frontal dementia<\/span><\/span>\n<\/div>\n<\/span>\n<div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n  <!---->\n<\/div>\n<\/li>\n<li class=\"list-item no-gutters\">\n  <!---->\n  <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-2185-icon style-local-6083-c39-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n  <span class=\"list-text d-block\"><span>Huntington&#8217;s disease (NH)<\/span><\/span>\n  <\/div>\n  <\/span>\n  <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n    <!---->\n  <\/div>\n<\/li>\n<li class=\"list-item no-gutters\">\n  <!---->\n  <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-2185-icon style-local-6083-c39-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n  <span class=\"list-text d-block\"><span>Mild Mental Discount<\/span><\/span>\n  <\/div>\n  <\/span>\n  <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\">\n    <!---->\n  <\/div>\n<\/li>\n<li class=\"list-item no-gutters\">\n  <!---->\n  <!----><span class=\"item-link no-gutters\"><div class=\"d-flex h-col no-gutters align-items-lg-center align-items-md-center align-items-center list-item-text-wrapper\"><div class=\"d-flex\"><span  class=\"h-svg-icon style-2185-icon style-local-6083-c39-icon\"><!--Icon by Font Awesome (https:\/\/fontawesome.com)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"check\" viewBox=\"0 0 1792 1896.0833\"><path d=\"M1671 566q0 40-28 68l-724 724-136 136q-28 28-68 28t-68-28l-136-136-362-362q-28-28-28-68t28-68l136-136q28-28 68-28t68 28l294 295 656-657q28-28 68-28t68 28l136 136q28 28 28 68z\"><\/path><\/svg><\/span><\/div>\n  <span class=\"list-text d-block\"><span>Underlying Mental Disorder<\/span><\/span>\n  <\/div>\n  <\/span>\n  <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center\" style=\"display: none;\">\n    <!---->\n  <\/div>\n  <div class=\"list-container-divider d-flex justify-content-lg-center justify-content-md-center justify-content-center last-el-spacer\"><\/div>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div data-colibri-id=\"6083-c40\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-2262 style-local-6083-c40 position-relative\">\n  <!---->\n  <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n    <!---->\n    <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-2263-outer style-local-6083-c41-outer\">\n      <div data-colibri-id=\"6083-c41\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-2263 style-local-6083-c41 position-relative\">\n        <!---->\n        <!---->\n        <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n          <!---->\n          <div data-colibri-id=\"6083-c42\" class=\"h-divider style-2197 style-local-6083-c42 position-relative h-element\">\n            <!----><span class=\"h-divider__line style-2197-line style-local-6083-c42-line style-2197-line style-local-6083-c42-line\"><\/span><\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>\n<\/div>\n<\/div>\n<div data-colibri-component=\"section\" data-colibri-id=\"6083-c47\" id=\"simantikotita\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-2166 style-local-6083-c47 position-relative\">\n  <!---->\n  <!---->\n  <div class=\"h-section-grid-container h-section-boxed-container\">\n    <!---->\n    <div data-colibri-id=\"6083-c48\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-2167 style-local-6083-c48 position-relative\">\n      <!---->\n      <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n        <!---->\n        <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-2169-outer style-local-6083-c49-outer\">\n          <div data-colibri-id=\"6083-c49\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-2169 style-local-6083-c49 position-relative\">\n            <!---->\n            <!---->\n            <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n              <!---->\n              <div data-colibri-id=\"6083-c50\" class=\"h-global-transition-all h-heading style-2190 style-local-6083-c50 position-relative h-element\">\n                <!---->\n                <div class=\"h-heading__outer style-2190 style-local-6083-c50\">\n                  <!---->\n                  <!---->\n                  <h4 class=\"\">Why is research into neurodegenerative diseases so important?<\/h4>\n                <\/div>\n              <\/div>\n              <div data-colibri-id=\"6083-c51\" class=\"h-text h-text-component style-2183 style-local-6083-c51 justify-text position-relative h-element\">\n                <!---->\n                <!---->\n                <div class=\"\">\n                  <p>Europe has a rapidly aging population. At present, 16% of the European population is over 65 and this figure is expected to reach 25% by 2030. Today in Europe, around \u20ac 130 billion is spent annually on caring for people with dementia.\n                    With the increase in the life expectancy of the population, the number of affected people is also increasing.<\/p>\n                  <p>NAs such as Alzheimer&#8217;s and Parkinson&#8217;s disease are debilitating and largely incurable conditions that are closely linked to age. Among these disorders, dementia is responsible for the greater burden of the disease, with Alzheimer&#8217;s\n                    disease and related disorders affecting more than 7 million people in Europe, and that number is expected to double every 20 years as the population ages.<\/p>\n                  <p>Symptoms of nerve disorders include decreased mobility, memory loss, mood swings, decreased speech and more.<\/p>\n                  <p>In the early stages, these dysfunctions do not affect patients significantly and they can continue to live an independent life. However, as the disease progresses, patients&#8217; quality of life decreases dramatically until they need full-time\n                    care. Consequently, there is a significant social and economic burden in the course of the disease.<\/p>\n                  <p>To date, there is a limited number of treatments used for NA and most of them treat only the symptoms and not the cause. In fact, no new drugs for Alzheimer&#8217;s disease have been approved in Europe in the last five years.<\/p>\n                  <p>With this in mind, successful treatments to delay or reduce the symptoms of these debilitating conditions are vital in reducing the detrimental effects they have on individuals, families, societies and economies.<\/p>\n                  <p>NA mimics cardiovascular disease and cancer as major causes of death. However, unlike cardiovascular disease and cancer, NA can not be cured or their progression can be significantly slowed down. While large investments have been made\n                    in diseases such as cancer and cardiovascular disease (and we have therefore seen significant improvements in treatment and patient outcomes), to date neurodegenerative diseases have not received the same level of funding, despite\n                    their large negative impact. in healthy years of life.<\/p>\n                <\/div>\n              <\/div>\n              <div data-colibri-id=\"6083-c52\" class=\"h-divider style-2195 style-local-6083-c52 position-relative h-element\">\n                <!----><span class=\"h-divider__line style-2195-line style-local-6083-c52-line style-2195-line style-local-6083-c52-line\"><\/span><\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>\n<div data-colibri-component=\"section\" data-colibri-id=\"6083-c57\" id=\"iatriki_akriveias\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-2174 style-local-6083-c57 position-relative\">\n  <!---->\n  <!---->\n  <div class=\"h-section-grid-container h-section-boxed-container\">\n    <!---->\n    <div data-colibri-id=\"6083-c58\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-2191 style-local-6083-c58 position-relative\">\n      <!---->\n      <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n        <!---->\n        <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-2192-outer style-local-6083-c59-outer\">\n          <div data-colibri-id=\"6083-c59\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-2192 style-local-6083-c59 position-relative\">\n            <!---->\n            <!---->\n            <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n              <!---->\n              <div data-colibri-id=\"6083-c60\" class=\"h-global-transition-all h-heading style-2193 style-local-6083-c60 position-relative h-element\">\n                <!---->\n                <div class=\"h-heading__outer style-2193 style-local-6083-c60\">\n                  <!---->\n                  <!---->\n                  <h4 class=\"\">What is precision medicine?<\/h4>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n    <div data-colibri-id=\"6083-c61\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-2175 style-local-6083-c61 position-relative\">\n      <!---->\n      <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n        <!---->\n        <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-2177-outer style-local-6083-c62-outer\">\n          <div data-colibri-id=\"6083-c62\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-2177 style-local-6083-c62 position-relative\">\n            <!---->\n            <!---->\n            <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n              <!---->\n              <div data-colibri-id=\"6083-c63\" class=\"h-text h-text-component style-2184 style-local-6083-c63 justify-text position-relative h-element\">\n                <!---->\n                <!---->\n                <div class=\"\">\n                  <p>Precision Medicine in SE refers to the better understanding of the clinical genetic phenotype of the patient, combining the pathology, biomarkers and genetic profile of the patient, with the aim of identifying pathological subtypes of\n                    diseases that can best respond to specific treatments.<\/p>\n                  <p>The development of a Medical Precision approach represents an excellent opportunity to identify preclinical stages of NA, to make an adequate differential diagnosis and to provide timely and optimal treatment instead of the traditional\n                    treatments commonly used in advanced disease.<span style=\"font-size: 101%;\"> <\/span><\/p>\n                  <p>Mission of Medical Precision:<\/p>\n                  <p>Translate research into clinical care by identifying patients who respond best to available and emerging therapies. Identification of new therapeutic goals based on a detailed understanding of the mechanisms of the disease.<\/p>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Description \u00a9 2021 Generally Neurodegenerative diseases, due to the aging of the population, are an ever-increasing burden for patients and carers. In these diseases, there is a progressively deteriorating clinical picture, due to a progressive degeneration of the neurons of the Central Nervous System. Such diseases are Alzheimer&#8217;s disease (AL), other forms of dementia, such [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/full-width-page.php","meta":{"footnotes":""},"class_list":["post-6083","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/neuropmnet.gr\/index.php?rest_route=\/wp\/v2\/pages\/6083","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuropmnet.gr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/neuropmnet.gr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/neuropmnet.gr\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/neuropmnet.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6083"}],"version-history":[{"count":3,"href":"https:\/\/neuropmnet.gr\/index.php?rest_route=\/wp\/v2\/pages\/6083\/revisions"}],"predecessor-version":[{"id":6247,"href":"https:\/\/neuropmnet.gr\/index.php?rest_route=\/wp\/v2\/pages\/6083\/revisions\/6247"}],"wp:attachment":[{"href":"https:\/\/neuropmnet.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6083"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}